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Title
How to Choose the Right Liquid Handling Automation Platform
Friday, January 11, 2019
Hal Wehrenberg
This article discusses some of the key points to consider when choosing a liquid handling platform for your laboratory.
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Improved Liquid Biopsies With Combined Digital PCR and Next-Generation Sequencing
Friday, February 19, 2016
George Karlin-Neumann
The discovery that circulating tumor DNA (ctDNA) can be found in the blood, urine and other bodily fluids of cancer patients has led to a new type of biopsy that bypasses surgery—liquid biopsy.
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Isothermal Titration Calorimetry: An Indispensable Tool for Biological Pathway Research and Drug Development
Monday, October 02, 2017
Verna Frasca
As our knowledge of the genetic and molecular basis of disease continues to grow, drug development programs focus increasingly on those proteins associated with disease states.
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Liquid Biopsy Solutions for Noninvasive Molecular Profiling
Monday, June 22, 2015
Michael Schwartz
Liquid biopsy offers the potential to understand and treat cancer in ways never before possible. The concept is simple: collect tumor DNA after it enters the peripheral blood circulation and identify...
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Liquid Handling Uses Acoustic Droplet Ejection for Improved Results
Monday, May 08, 2017
Mark Fischer-Colbrie
Acoustic drop ejection systems can pave the way for entirely new applications, bringing higher throughput and greater flexibility to many areas of biology.
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Long-Range Genomics Is Reviving a Lost Art
Wednesday, July 26, 2017
Chris Boles
The instrument described here was designed to treat DNA gently enough that users can prepare libraries of extremely large fragments directly from blood samples, bacterial and tissue cultures, or other...
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Manufacturing Considerations for IVD Reagents Used in Clinical Chemistry and Special Chemistry Laboratories
Tuesday, July 25, 2017
Robert J. Janetschek
Julia Nisbet-Fahy
Andrew Whitehouse
To produce diagnostic reagents that meet current and future demands requires a knowledge, understanding, and appreciation of the various reagents used for clinical testing applications.
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Micro RNA Profiling with a Multiplexed Assay
Monday, March 03, 2014
Mark Santos
From the discovery of new miRNAs to clarifying their biological roles and utility as biomarkers, micro RNA (miRNA)-based research is undergoing a period of change. Rigorous methods are therefore ...
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Next-Generation Sequencing for Disease Biomarkers
Monday, December 15, 2014
Darren Lee
Next-generation sequencing (NGS) is beginning to provide powerful insights into genetic mutations and molecular networks underlying disease for a broad set of genes. NGS technologies promise to ...
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Powering Preclinical Imaging With Multi-Modal Positron Emission Tomography
Friday, June 07, 2019
Sonica Van Wyk
Multi-modal systems make it simple for researchers to combine the benefits of PET imaging with CT, SPECT, and MRI technology for optimal imaging results.
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Reference Standards Address Technical Challenges in DNA Resequencing
Tuesday, August 04, 2015
Natalie A. LaFranzo
The extensive workflow required to analyze DNA samples using next-generation sequencing (NGS) leaves many opportunities for the introduction of variability.
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Special Protein Testing in the Clinical Laboratory: Overview of Available Assays
Friday, July 22, 2016
Robert J. Janetschek
The proteins found within the human machine are, quite literally, the building blocks of life: individual cells contain more than 5000 individual proteins.
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Theory and Practical Applications of Automation Solutions in Analytical Measurements
Wednesday, July 24, 2019
Heidi Fleischer
Kerstin Thurow
Automated systems for sample preparation and analytical measurements must follow special protocols due to their complex process structure with multiple subprocesses.
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Top-Down Proteomics: An Emerging Technology Propelled by Mass Spectrometry
Wednesday, July 26, 2017
Rohan A. Thakur
Rapid developments in mass spectrometry technology facilitate innovative solutions to the challenges in top-down proteomics.
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Urinary Drug Testing: Small Changes for Big Improvements in Sensitivity
Tuesday, September 27, 2016
Jenny Cybulski
An oversight or mistake in drug testing can have dire consequences—a positive drug test can ruin the possibility of employment, turn an accident into a lawsuit, or cause a physician to discontinue ...
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Vaccine Storage: Keeping Vaccines Safe When They Are In Highest Demand
Friday, January 04, 2013
Alex Esmon
Flu season is upon us and laboratories are doing their part to make sure vaccines are prepared and ready for distribution. One of the biggest problems faced by laboratories and clinics during flu ...
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With Smart Automation, Clinical Labs Can Generate Higher-Quality Results in Less Time
Friday, January 11, 2019
Adrian Russell
Automation streamlines operations and gives technicians more time to develop assays and evaluate new platforms that can help improve patient outcomes.
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